TORONTO / LONDON (IT BOLTWISE) – Onco-Innovations and Dalton Pharma Services have made significant progress in the development of cancer therapies. By optimizing the PNKP inhibitor technology A83B4C63, they are setting new standards in clinical research. These innovations could significantly improve the efficiency and precision of future clinical trials.
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Onco-Innovations, a leading Canadian biotechnology company, has made significant progress in the development of cancer therapies in collaboration with Dalton Pharma Services. The focus is on the PNKP inhibitor technology, known as A83B4C63. This technology could revolutionize the way cancer is treated by significantly improving the precision and efficiency of clinical trials.
Dalton Pharma Services has focused on process optimization and scaling of the A83B4C63 synthesis technology. A particular focus is on ensuring technological maturity under non-GMP conditions. This phase is crucial as it represents a bridge between laboratory synthesis and preclinical production at a scalable level. This paves the way to support upcoming GMP production, which is essential for the provision of clinical material and the preparation of an Investigational New Drug (IND) application.
Dalton’s expertise in process scaling and analytical technologies is central to this advancement. At their state-of-the-art facility in Tokyo, specialized pilot technologies are used to successfully synthesize the first intermediate products. These milestones are based on thorough safety and risk assessments of the active ingredient, ensuring a reproducible and safe manufacturing process that meets top international standards.
Thomas O’Shaughnessy, CEO of Onco-Innovations, emphasized the importance of the breakthroughs achieved with Dalton. These advances not only strengthen clinical development capabilities, but also create a solid foundation for future innovations in cancer treatment. Both companies are committed to developing innovative solutions for the medical sector to improve the quality of life of cancer patients worldwide.
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