LONDON (IT BOLTWISE) – A new clinical trial shows that a monthly injection of tezepelumab could help people with severe asthma avoid daily steroid tablets. This development could improve the quality of life of millions of asthmatics worldwide and reduce the side effects of long-term steroid use.
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A new clinical trial has shown that a monthly injection of tezepelumab could help people with severe asthma avoid daily steroid tablets. This treatment could improve the quality of life of millions of asthmatics worldwide by reducing the side effects of long-term steroid use. Tezepelumab, also known as Tezspire and made by AstraZeneca, blocks a protein linked to airway inflammation.
The study, led by King’s College London, included nearly 300 adults with severe, uncontrolled asthma. These patients took between 5 mg and 40 mg steroid tablets daily. After a year of treatment with monthly injections, more than half of the participants were able to stop their steroid medication completely without their asthma worsening. Almost 90% reduced their steroid dosage to low levels.
The results of the study, published in The Lancet Respiratory Medicine, also showed that tezepelumab significantly improved asthma symptoms, lung function and overall quality of life. During the study, two-thirds of the patients had no asthma attacks. These results were presented at the British Thoracic Society winter meeting.
Dr. Samantha Walker from Asthma + Lung UK described the results as an encouraging step forward for the future of asthma treatment. She highlighted the need for further research to secure funding for lung research, as lung disease remains the third leading cause of death in the UK.
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